VIP is a naturally occurring neuropeptide with widespread effects on smooth muscle relaxation, vasodilation, and immune regulation. It has
been investigated as a therapeutic candidate in inflammatory, pulmonary, and gastrointestinal disorders due to its potent anti-inflammatory
and cytoprotective actions.
Key Benefits
• Anti-Inflammatory: Modulates immune response, reduces cytokine activity.
• Pulmonary Support: Potential use in pulmonary arterial hypertension (PAH) and asthma.
• Neuroprotective Effects: Investigated for neurodegenerative and cognitive disorders.
• Vascular Health: Promotes vasodilation and blood flow.
Clinical Findings
• Studies show VIP analogs improve pulmonary function in PAH models.
• Early trials suggest potential benefits in inflammatory bowel disease and autoimmune conditions.
• Research ongoing in neuroprotection and cognitive function.
Safety & Tolerability
• Generally well tolerated in limited clinical studies.
• Possible effects: flushing, headache, mild hypotension due to vasodilation.
• Long-term human safety profile not fully established.
Dosing
• No standardized dosing regimen.
• Investigational use in trials via subcutaneous, inhaled, or intravenous routes.
• Protocols vary by research context.
For research and informational purposes only – not for medical use.




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